Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > NIH recognizes Clemson nanotechnology for molecule tracking

Abstract:
The National Institutes of Health has awarded two Clemson chemistry faculty members nearly $1 million to detect, track and image the interior of cells. Jason McNeill and Ken Christensen will receive the $960,000 grant to develop polymer dot nanoparticles for tracking single molecules in live cells.

NIH recognizes Clemson nanotechnology for molecule tracking

CLEMSON, SC | Posted on October 31st, 2007

The development of techniques for following individual molecules within cells is important because scientists could use this technology to determine the body's defenses against invading viruses and bacteria or how proteins operate within the cell. The technology also could help doctors pinpoint the exact location of cancer cells in order to better focus treatment and minimize damage to healthy tissue. Other possible targets of investigation include plaques and fibrils in the brain associated with Alzheimer's disease and mad cow disease.

For the last decade, scientists around the globe have worked to develop and refine highly fluorescent nanoparticles that light up when bathed with laser light, enabling scientists to pinpoint the location of an individual molecule inside a living cell or tissue.

Recently, Clemson chemists developed novel, highly fluorescent nanoparticles called "polymer dots" that can be attached to individual proteins, DNA or invading microbes. According to chemist Jason McNeill, the polymer dot particles are hundreds or thousands of times brighter than conventional fluorescent dyes.

Tissue cells that protect from infection loaded with nanoparticles."We were initially interested in developing polymer semiconductor nanoparticles for making inexpensive, highly efficient solar cells and light-emitting displays. When we aimed a laser at the particles in a microscope, we were surprised to see individual particles light up very brightly," said McNeill.

"When I heard about these extremely bright particles, my group was very interested in working with Dr. McNeill to push this technology into live cell imaging," said Christensen. "Biology is often driven by new discoveries in chemistry and physics and these polymer dots will definitely impact our studies of cellular biology."

The two chemists credit the highly collaborative, multidisciplinary environment at Clemson as a key factor in this new frontier in nanotechnology.

Details of the nanoparticle technology were recently presented at the 2007 national meeting of the American Chemical Society in Boston and have been published in the Journal of the American Chemical Society, Langmuir and in the Journal of Physical Chemistry.

Editors: This material is based upon work supported by the NSF/EPSCoR under grant numbers 2001RII-EPS-0132573 and 2004RII-EPS-0447660, NSF CAREER grant number CHE-0547846 and NIH grant number 1R01GM081040. Any opinions, findings and conclusions or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation or the National Institutes of Health.

####

About Clemson University
Today, Clemson is redefining the term “top-tier research university” by combining the best of two models: the scientific and technological horsepower of a major research university and the highly engaged academic and social environment of a small college. With a distinctive governance system that fosters stability in leadership, unique college structures that create an unmatched climate for collaboration, and a driven, competitive spirit that encourages faculty, staff and students to embrace bold, sometimes audacious, goals, Clemson has set its sights on being one of the nation’s top-20 public universities by 2011.

For more information, please click here

Contacts:
Jason McNeill
(864) 656-4065


WRITER: Susan Polowczuk
(864) 656-2063

Copyright © Clemson University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Govt.-Legislation/Regulation/Funding/Policy

Physicists decipher electronic properties of materials in work that may change transistors December 6th, 2016

Construction of practical quantum computers radically simplified: Scientists invent ground-breaking new method that puts quantum computers within reach December 5th, 2016

Shape matters when light meets atom: Mapping the interaction of a single atom with a single photon may inform design of quantum devices December 4th, 2016

Research Study: MetaSOLTM Shatters Solar Panel Efficiency Forecasts with Innovative New Coating: Coating Provides 1.2 Percent Absolute Enhancement to Triple Junction Solar Cells December 2nd, 2016

Discoveries

ANU invention to inspire new night-vision specs December 7th, 2016

Leti IEDM 2016 Paper Clarifies Correlation between Endurance, Window Margin and Retention in RRAM for First Time: Paper Presented at IEDM 2016 Offers Ways to Reconcile High-cycling Requirements and Instability at High Temperatures in Resistive RAM December 6th, 2016

Tokyo Institute of Technology research: 3D solutions to energy savings in silicon power transistors December 6th, 2016

Physicists decipher electronic properties of materials in work that may change transistors December 6th, 2016

Announcements

ANU invention to inspire new night-vision specs December 7th, 2016

Arrowhead Pharmaceuticals to Webcast Fiscal 2016 Year End Results December 7th, 2016

Journal Nanotechnology Progress International (JONPI), newest edition out December 7th, 2016

In IEDM 2016 Keynote, Leti CEO Says ‘Hyperconnectivity’, Human-focused Research and the IOT Promise Profound, Positive Changes December 7th, 2016

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Physicists decipher electronic properties of materials in work that may change transistors December 6th, 2016

Shape matters when light meets atom: Mapping the interaction of a single atom with a single photon may inform design of quantum devices December 4th, 2016

Quantum obstacle course changes material from superconductor to insulator December 1st, 2016

'Back to the Future' inspires solar nanotech-powered clothing November 15th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project