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Maleimidopropionyl-PEG significantly enhances assay and drug optimisation
Following successful customer trials, the Scandinavian-based PEG specialist Polypure has launched its latest monodispersed PEG derivative - Maleimidopropionyl-PEG NHS ester. This heterobifunctional PEG is designed to improve crosslinking between compounds carrying amino groups and thiol functions and is attracting widespread interest from both diagnostic and pharmaceutical developers.
According to Polypure Marketing Director Magali Le Bomin, this new PEG fully demonstrates the increasingly acknowledged benefits of monodispersed PEGs: "The polymer homogeneity achieved by using our patented Sample Displacement Chromatographic purification method ensures a high level of functional integrity. Likewise, the single molecular weight avoids the characterisation problems of polydispersed polymer mixtures. Looking at applications, for diagnostics we can significantly improve cross-linking, binding and lots reproducibility. Similarly for pharmaceuticals, the extended PEG space length enhances the solubility of poorly soluble drugs. Furthermore, there is the overriding benefit of being able to reduce diagnostic and drug design complexity which has a significant impact on development, regulatory and production times."
About Polypure As
The Scandinavian based company Polypure is a world leader in the design and manufacture of monodispersed PEG derivatives for advanced technologies. Our quality standards ensure their successful use in research and industrial applications in nanotechnology, biotechnology and in pharmaceutical sciences. The compounds are produced by using a proprietary purification technology that is both cost efficient and can be readily scaled up to meet an increase in product demand.
The company has been in operation since 1999. The business strategy relies on a focused product development to meet the demand for state of the art derivatives. We support the global market with our stock items, as well as custom synthesis products for specific applications. Our standard PEG catalogue products are distributed by major chemical distributors and are represented worldwide through agents in Europe, USA and Japan.
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Magali Le Bomin
Oslo Research Park, N-0349
Tel ++47 22 95 83 29
Tel +44 (0) 7711821527
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