Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Advances in Drug Discovery Technologies Fuelling Development of Anti-Diabetic Therapies

Abstract:
Rising knowledge of metabolic pathways at genetic, cellular, and molecular levels is giving rise to more focused molecular drug targets, reports a new analysis from Frost & Sullivan.

Advances in Drug Discovery Technologies Fuelling Development of Anti-Diabetic Therapies

Palo Alto, CA | Posted on September 25th, 2007

This, coupled with significant advances in drug discovery technologies is rekindling interest in the immense potential of therapeutic diabetes drugs, resulting in a multiplicity of pharmaceutical drug targets.

"Toxic side effects of conventional oral hypoglycemic drugs is driving the need for novel drugs with better safety, efficacy, and tolerability profile, which would have a different mechanism of action altogether," says Frost & Sullivan Research Analyst Sangeetha Prabakar. "The pharmaceutical sector is likely to witness further influx of drugs that could replicate the normal insulin activity thereby, enhancing the biosynthesis of insulin in a patient."

If you are interested in a virtual brochure, which provides manufacturers, end users, and other industry participants an overview of the latest analysis of the Emerging Therapies for Diabetes, then send an email to Melina Trevino - Corporate Communications at melina.trevino[.]frost.com with the following information: your full name, company name, title, telephone number, email address, city, state, and country. We will send you the information via email upon receipt of the above information.

The imminent commercialization of inhalable and oral insulin as well as insulin patches can replace insulin injections. Another trend in insulin therapies is the increased availability of insulin types that suit patient needs such as rec-human insulin, regular, lente, lispro, and 70/30, each with different action, peak activity, and duration.

The majority of insulin used is genetically engineered human insulin and is likely to replace all other forms of insulin in the future. These non-invasive delivery mechanisms are likely to enhance patient convenience and adherence to insulin therapy, which can lead to increased insulin market demands.

Advances in encapsulation technologies, bio-sensing devices, and insulin delivery methods are driving innovations in islet cell transplant and artificial pancreas. Moreover, the two therapies have a huge potential of offering a long-term cure for type-1 diabetes.

If commercialized successfully, the islet cell therapies will likely replace whole pancreas transplants in the future. In this therapy, insulin-producing islet cells are injected into the liver through a simple non-surgical procedure. In the future patients might prefer islet cell therapies to whole organ transplant considering the risks of adverse immune reactions due to foreign tissue rejection, requiring a lifetime of immunosuppressive treatment.

Another recent development has been the artificial pancreas, which consists of a glucose sensor, insulin pump, and computer software that connects the two to enable automated monitoring, dose adjustments, and insulin infusion without patient intervention.

Major device manufacturers and technology companies and institutions around the world have already received considerable amounts of funding for expediting the development, testing, and commercialization of such devices. The application of nanotechnology in future glucose sensing devices, artificial pancreas research, and gene delivery techniques can significantly boost further developments in this sector.

However, huge costs, apprehensions regarding new drug prescription, and self-medication pose significant challenges. Low-income groups in developing countries, unable to afford expensive anti-diabetic drugs, look for low-priced and easily available alternative and complementary medicines. This brings down the market demand for existing as well as incoming drugs. Hence, drug manufactures can focus on uniform availability of beneficial drugs by reducing the selling price.

As medical practitioners require periodic updates about new medications, their contraindications, costs, and efficacies, the pharmaceutical industry will benefit by keeping physicians informed.

"It is crucial to increase patient awareness of the disease complications and the importance of continuous and regular monitoring of the disease," notes Prabakar. "Educators also need to focus on the advances in drug discovery and delivery technologies, importance of self-management goals, monitoring devices, and the availability and usage of user-friendly as well as home-based testing tools, by providing instruction and support through regular awareness campaigns."

Emerging Therapies for Diabetes is part of the Technical Insights - Healthcare vertical subscription service. The study examines pharmacotherapy, insulin therapy, pancreas transplant, islet cell transplant, artificial pancreas, and gene therapy. Interviews are available to the press.

Technical Insights is an international technology analysis business that produces a variety of technical news alerts, newsletters, and research services.

####

About Frost & Sullivan
Frost & Sullivan, a global growth consulting company, has been partnering with clients to support the development of innovative strategies for more than 40 years. The company's industry expertise integrates growth consulting, growth partnership services, and corporate management training to identify and develop opportunities. Frost & Sullivan serves an extensive clientele that includes Global 1000 companies, emerging companies, and the investment community by providing comprehensive industry coverage that reflects a unique global perspective and combines ongoing analysis of markets, technologies, econometrics, and demographics.

For more information, please click here

Contacts:
Melina Trevino
210.247.2440

Copyright © Newswire Today

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Nanomedicine

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Arrowhead Presents New Clinical Data Demonstrating a Sustained Host Response in Hepatitis B Patients Following RNAi Therapy Up to 5.0 log10 reduction in HBsAg observed; data presented at HEP DART 2017 December 6th, 2017

Announcements

A new product to help combat mouldy walls, thanks to technology developed at the ICN2 December 14th, 2017

Sandia researchers make solid ground toward better lithium-ion battery interfaces: Reducing the traffic jam in batteries December 13th, 2017

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

Columbia engineers create artificial graphene in a nanofabricated semiconductor structure: Researchers are the first to observe the electronic structure of graphene in an engineered semiconductor; finding could lead to progress in advanced optoelectronics and data processing December 13th, 2017

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

UCLA chemists synthesize narrow ribbons of graphene using only light and heat: Tiny structures could be next-generation solution for smaller electronic devices December 8th, 2017

Device makes power conversion more efficient: New design could dramatically cut energy waste in electric vehicles, data centers, and the power grid December 8th, 2017

Creating a new kind of metallic glass December 7th, 2017

Copper will replace toxic palladium and expensive platinum in the synthesis of medications: The effectiveness of copper nanoparticles as a catalyst has been proven December 5th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project