Home > Press > Keck Foundation funds UO's bio-nanomaterials research
The University of Oregon has received a $1.6 million grant from the W.M. Keck Foundation to explore the biological effects of exposure to precisely engineered nanoparticles that are being designed for diagnostic and therapeutic uses.
Keck Foundation funds UO's bio-nanomaterials research
EUGENE, OR | Posted on September 10th, 2007
The three-year grant from the Keck Foundation's medical research program will involve six researchers: Mark Lonergan, Jim Hutchison and Andy Berglund, all UO professors of chemistry; UO biology professors Karen Guillemin and Eric Johnson; and Robert Tanguay, a professor of environmental and molecular toxicology at Oregon State University.
All are members of the Safer Nanomaterials and Nanomanufacturing Initiative (SNNI), directed by Hutchison and part of the Oregon Nanoscience and Microtechnologies Institute (ONAMI).
"This award from the Keck Foundation puts us at the forefront of this quickly developing and promising field of nanotechnology," said UO President Dave Frohnmayer. "Nanotechnology has been described as being in its discovery phase. This newly funded project means the University of Oregon, Oregon State University and the state, through ONAMI - Oregon's first Signature Research Center - can help build a green roadmap for the field."
The interdisciplinary project is designed to help researchers understand potential biological interactions of engineered nanomaterials and develop design rules for the development of nanoparticles with enhanced biological properties. The researchers will produce specific structures of nanomaterials, investigate their interactions with biological systems and then design new materials and nanoparticle libraries that have specific biological responses.
The biological testing will involve laboratory experiments using zebrafish, an invertebrate animal model system that was first developed for research at the University of Oregon. With zebrafish, researchers can monitor tissue-specific interactions with nanoparticles, developmental and acute toxicity, and the impacts of exposure on gene regulation.
The researchers will address existing gaps in the field, from the basic construction of nanoparticles to how they interface with biological cells. As the foundation for the project, the group will build upon the library of gold nanoparticles created by Hutchison using his patented green-chemistry approach.
"Our goal is to define the important interactions at the bio-nano interface, as well as the ground rules for producing nanoparticles that have very fine-tuned objectives," Hutchison said. "The end results could lead to a variety of future therapeutics that specifically seek out and destroy cancer cells or promote desired cell growth for tissue regeneration."
The Keck Foundation funds will cover just under $1 million in graduate and faculty research, with the remainder going toward the purchase of equipment and space for housing it. The instruments will go into the Lorry I. Lokey Laboratories, the underground portion of the Integrated Science Complex, where some of the project's research will be conducted.
The W.M. Keck Foundation, based in Los Angeles, is one of the nation's largest philanthropic organizations. Established in 1954 by William Myron Keck, the founder of Superior Oil Co., the foundation provides funds primarily in the areas of medical research, science and engineering.
About University of Oregon
The University of Oregon is a world-class teaching and research university located in the beautiful Willamette Valley of Oregon. The UO offers a broad spectrum of opportunities for learning in the liberal arts and professional programs in architecture, arts, business, education, journalism, law, and music and dance. In the classrooms and laboratories, students are inspired by a faculty of prominent scholars and work side by side with eminent researchers involved in breakthrough discoveries. At the UO, both students and faculty members reach out to make connections that serve communities from small local groups to large international organizations. Explore the University of Oregon. You will like what you find.
Contact: Jim Barlow
Source: Jim Hutchison
professor of chemistry
If you have a comment, please Contact
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Tissue regeneration using anti-inflammatory nanomolecules August 22nd, 2014
A breakthrough in imaging gold nanoparticles to atomic resolution by electron microscopy August 22nd, 2014
Malvern’s Dr Alan Rawle talks TLAs in plenary lecture at Particulate Systems Analysis conference August 21st, 2014
Water window imaging opportunity: A new theoretical study elucidates mechanisms that could help in producing coherent radiations, ultimately promoting high-contrast imaging of biological samples August 21st, 2014
Sunblock poses potential hazard to sea life August 20th, 2014
Analytical solutions from Malvern Instruments support University of Wisconsin-Milwaukee researchers in understanding environmental effects of nanomaterials July 30th, 2014
NNCO Announces an Interactive Webinar: Progress Review on the Coordinated Implementation of the National Nanotechnology Initiative 2011 Environmental, Health, and Safety Research Strategy July 23rd, 2014
Development of an interactive tool for the implementation of environmental legislation for nanoparticles manufacturers July 4th, 2014
Rice physicist emerges as leader in quantum materials research: Nevidomskyy wins both NSF CAREER Award and Cottrell Scholar Award August 20th, 2014
Oxford Instruments Asylum Research Receives the 2014 Microscopy Today Innovation Award for blueDrive Photothermal Excitation August 18th, 2014
AQUANOVA receives Technology Leadership Award 2014 FROST & SULLIVAN honors NovaSOL® Technology again August 12th, 2014
Focal blood-brain-barrier disruption with high-frequency pulsed electric fields August 12th, 2014