Nanotechnology Now

Our NanoNews Digest Sponsors





Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Yale Scientists Use Nanotechnology to Fight E. coli

E.coli incubated for one hour on support matrix in the absence (1) or in the presence (2) of nanotubes. (Elimelech/Yale)
E.coli incubated for one hour on support matrix in the absence (1) or in the presence (2) of nanotubes. (Elimelech/Yale)

Abstract:
Single-walled carbon nanotubes (SWCNTs) can kill bacteria like the common pathogen E. coli by severely damaging their cell walls, according to a recent report from Yale researchers in the American Chemical Society (ACS) journal Langmuir.

Yale Scientists Use Nanotechnology to Fight E. coli

NEW HAVEN, CT | Posted on September 3rd, 2007

"We began the study out of concerns for the possible toxicity of nanotubes in aquatic environments and their presence in the food chain," said Menachem Elimelech, professor and chair of chemical and environmental engineering at Yale and senior author on the paper. "While nanotubes have great promise for medical and commercial applications there is little understanding of how they interact with humans and the environment."

"The nanotubes are microscopic carbon cylinders, thousands of times smaller than a human hair that can be easily taken up by human cells," said Elimelech. "We wanted to find out more about where and how they are toxic."

This "nanoscience version of a David-and-Goliath story" was hailed in an ACS preview of the work as the first direct evidence that "carbon nanotubes have powerful antimicrobial activity, a discovery that could help fight the growing problem of antibiotic resistant infections."

Using the simple E. coli as test cells, the researchers incubated cultures of the bacteria in the presence of the nanotubes for up to an hour. The microbes were killed outright - but only when there was direct contact with aggregates of the SWCNTs that touched the bacteria. Elimelech speculates that the long, thin nanotubes puncture the cells and cause cellular damage.

The study ruled out metal toxicity as a source of the cell damage. To avoid metal contaminants in commercial sources, the SWCNTs were rigorously synthesized and purified in the laboratory of co-author Professor Lisa Pfefferle.

"We're now studying the toxicity of multi-walled carbon nanotubes and our preliminary results show that they are less toxic than SWCNTs," Elimelech said. "We are also looking at the effects of SWCNTs on a wide range of bacterial strains to better understand the mechanism of cellular damage."

Elimelech projects that SWCNTs could be used to create antimicrobial materials and surface coatings to improve hygiene, while their toxicity could be managed by embedding them to prevent their leaching into the environment.

Other authors on the paper are Seoktae Kang and Mathieu Pinault. The project was funded by a research grant from the National Science Foundation.

Citation: Langmuir 23(17): 8670-8673 (August 28, 2007).

####

About Yale University
Yale University comprises three major academic components: Yale College (the undergraduate program), the Graduate School of Arts and Sciences, and the professional schools. In addition, Yale encompasses a wide array of centers and programs, libraries, museums, and administrative support offices. Approximately 11,250 students attend Yale.

For more information, please click here

Contacts:
Janet Rettig Emanuel
203-432-2157

Copyright © Yale University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Nanomedicine

NYU Researchers Break Nano Barrier to Engineer the First Protein Microfiber October 23rd, 2014

Iranian Scientists Apply Nanotechnology to Produce Surgery Suture October 23rd, 2014

RF Heating of Magnetic Nanoparticles Improves the Thawing of Cryopreserved Biomaterials October 23rd, 2014

Sopping up proteins with thermosponges: Researchers develop novel nanoparticle platform that proves effective in delivering protein-based drugs October 22nd, 2014

Discoveries

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Iranian, Malaysian Scientists Study Nanophotocatalysts for Water Purification October 23rd, 2014

Nanoparticle technology triples the production of biogas October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

Announcements

Haydale Secures Exclusive Development and Supply Agreement with Tantec A/S: New reactors to be built and commissioned by Tantec A/S represent another step forward towards the commercialisation of graphene October 24th, 2014

QuantumWise guides the semiconductor industry towards the atomic scale October 24th, 2014

Advancing thin film research with nanostructured AZO: Innovnano’s unique and cost-effective AZO sputtering targets for the production of transparent conducting oxides October 23rd, 2014

Strengthening thin-film bonds with ultrafast data collection October 23rd, 2014

NanoNews-Digest
The latest news from around the world, FREE





  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More














ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE