Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > News > Nanoparticle-enabled peptide delivery triggers tumor regression

June 15th, 2007

Nanoparticle-enabled peptide delivery triggers tumor regression

Abstract:
Cells possess a variety of ways of dealing with mutations that can cause them to grow uncontrollably and eventually form a tumor. The tumor suppressor gene p53 plays a critical role in these cancer prevention processes, largely by triggering a form a cell death known as apoptosis.

Many research groups are working to develop strategies for boosting p53 levels in precancerous and malignant cells. However, since approximately half of all cancers have mutations that prevent p53 from triggering apoptosis, these approaches are limited in their effectiveness in treating cancer.

To overcome the mechanisms that cancer cells develop to circumvent p53's efforts to kill those cells, a team of investigators at the Beatson Institute for Cancer Research in Glasgow, Scotland, have turned to a related gene, known as p73, that also trigger apoptosis by a more circuitous but equally effective biochemical process. In a study published in the Journal of Clinical Investigation, this team, led by Kevin Ryan, Ph.D., found that a protein designed to turn on p73, delivered to tumors using a nanoparticle, kills both primary tumor cells and those that have spread from the original tumor.

Source:
news-medical.net

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Nanomedicine

Research reveals how our bodies keep unwelcome visitors out of cell nuclei November 24th, 2014

ASU, IBM move ultrafast, low-cost DNA sequencing technology a step closer to reality November 24th, 2014

An Inside Job: UC-Designed Nanoparticles Infiltrate, Kill Cancer Cells From Within November 24th, 2014

Iran Exports Nanodrugs to Syria November 24th, 2014

Discoveries

Researchers engineer improvements of technology used in digital memory November 24th, 2014

Research reveals how our bodies keep unwelcome visitors out of cell nuclei November 24th, 2014

ASU, IBM move ultrafast, low-cost DNA sequencing technology a step closer to reality November 24th, 2014

An Inside Job: UC-Designed Nanoparticles Infiltrate, Kill Cancer Cells From Within November 24th, 2014

Announcements

Research reveals how our bodies keep unwelcome visitors out of cell nuclei November 24th, 2014

ASU, IBM move ultrafast, low-cost DNA sequencing technology a step closer to reality November 24th, 2014

An Inside Job: UC-Designed Nanoparticles Infiltrate, Kill Cancer Cells From Within November 24th, 2014

Cooling with the coldest matter in the world November 24th, 2014

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More












ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE