Nanotechnology Now







Heifer International

Wikipedia Affiliate Button


DHgate

Home > News > Nanoparticle-enabled peptide delivery triggers tumor regression

June 15th, 2007

Nanoparticle-enabled peptide delivery triggers tumor regression

Abstract:
Cells possess a variety of ways of dealing with mutations that can cause them to grow uncontrollably and eventually form a tumor. The tumor suppressor gene p53 plays a critical role in these cancer prevention processes, largely by triggering a form a cell death known as apoptosis.

Many research groups are working to develop strategies for boosting p53 levels in precancerous and malignant cells. However, since approximately half of all cancers have mutations that prevent p53 from triggering apoptosis, these approaches are limited in their effectiveness in treating cancer.

To overcome the mechanisms that cancer cells develop to circumvent p53's efforts to kill those cells, a team of investigators at the Beatson Institute for Cancer Research in Glasgow, Scotland, have turned to a related gene, known as p73, that also trigger apoptosis by a more circuitous but equally effective biochemical process. In a study published in the Journal of Clinical Investigation, this team, led by Kevin Ryan, Ph.D., found that a protein designed to turn on p73, delivered to tumors using a nanoparticle, kills both primary tumor cells and those that have spread from the original tumor.

Source:
news-medical.net

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Nanomedicine

Patent for the Novel Cancer Therapies – Ceramide Nanoliposomes March 4th, 2015

Arrowhead to Present at 2015 Barclays Global Healthcare Conference March 4th, 2015

Democratizing synthetic biology: New method makes research cheaper, faster, and more accessible March 3rd, 2015

Pens filled with high-tech inks for do-it-yourself sensors March 3rd, 2015

Discoveries

American Chemical Society Presidential Symposia: nanoscience, international chemistry March 5th, 2015

Experiment and theory unite at last in debate over microbial nanowires: New model and experiments settle debate over metallic-like conductivity of microbial nanowires in bacterium March 4th, 2015

Magnetic vortices in nanodisks reveal information: Researchers from Dresden and Jülich use microwaves to read out information from smallest storage devices March 4th, 2015

CiQUS researchers obtain high-quality perovskites over large areas by a chemical method March 4th, 2015

Announcements

Get ready for NanoDays! March 5th, 2015

American Chemical Society Presidential Symposia: nanoscience, international chemistry March 5th, 2015

CiQUS researchers obtain high-quality perovskites over large areas by a chemical method March 4th, 2015

Arrowhead to Present at 2015 Barclays Global Healthcare Conference March 4th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2015 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE