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Home > News > New coating enables quantum dots to penetrate cells

June 12th, 2007

New coating enables quantum dots to penetrate cells

Abstract:
In just the few years since their discovery, quantum dots have become an important tool for imaging events occurring on the outside of cells and for identifying specific molecules in "fixed" cells. Researchers have found it difficult, however, to use quantum dots for molecular imaging inside of living cells, largely because these fluorescent nanoparticles tend to clump together inside organelles such as endosomes and lysosomes. But by using a positively charged polymer coating, investigators at the Emory-Georgia Tech Nanotechnology Center for Personalized and Predictive Oncology have developed quantum dots that penetrate the cell membrane, break open endosomes and lysosomes, and avoid clumping.

Source:
nanowerk.com

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