Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > Press > IBM Milestone Brings MRI Technology to the Nanoscale

 IBM's NANO MRI: The heart of IBM's 'nano-MRI' microscope measures
just twelve hundredths of a millimeter in length and a tiny one
ten-thousandth of a millimeter thick. This technique brings MRI
capability to the nanoscale level for the first time, a major
milestone in the quest to build a microscope that could 'see'
individual atoms in 3-D. Future applications could include
understanding how individual proteins interact with drugs, and
analyzing computer circuits only a few atoms wide.
IBM's NANO MRI: The heart of IBM's 'nano-MRI' microscope measures just twelve hundredths of a millimeter in length and a tiny one ten-thousandth of a millimeter thick. This technique brings MRI capability to the nanoscale level for the first time, a major milestone in the quest to build a microscope that could 'see' individual atoms in 3-D. Future applications could include understanding how individual proteins interact with drugs, and analyzing computer circuits only a few atoms wide.

Abstract:
Achievement Marks Significant Advance Toward the Imaging of Molecular Structures

IBM Milestone Brings MRI Technology to the Nanoscale

SAN JOSE, CA | Posted on April 22nd, 2007

IBM (NYSE: IBM) today announced that researchers at its Almaden Research Center have demonstrated magnetic resonance imaging (MRI) techniques to visualize nanoscale objects. This technique brings MRI capability to the nanoscale level for the first time and represents a major milestone in the quest to build a microscope that could "see" individual atoms in three dimensions.

Using Magnetic Resonance Force Microscopy (MRFM), IBM researchers have demonstrated two-dimensional imaging of objects as small as 90 nanometers, a key advancement on the path of 3D imaging at the atomic scale. Such imaging could ultimately provide a better understanding of how proteins function, which in turn may lead to more efficient drug discovery and development.

"Our ultimate goal is to perform three-dimensional imaging of complex structures such as molecules with atomic resolution," said Dan Rugar, manager, Nanoscale Studies, IBM Research. "This would allow scientists to study the atomic structures of molecules -- such as proteins -- which would represent a huge breakthrough in structural molecular biology."

MRFM offers imaging sensitivity that is 60,000 times better than current magnetic resonance imaging (MRI) technology. MRFM uses what is known as force detection to overcome the sensitivity limitations of conventional MRI to view structures that would otherwise be too small to be detected.

To achieve this, the research team developed specialized magnetic tips for their microscope, optimizing their ability to manipulate and detect the very weak magnetism of atomic nuclei. Conventional medical MRI typically operates on a scale at least 1,000 times coarser; even the most specialized MRI microscopy is limited to about 3 micrometers, or 3,000 nanometers.

This achievement could eventually have major impact on the study of materials -- ranging from proteins and pharmaceuticals to integrated circuits -- for which a detailed understanding of the atomic structure is essential. Knowing the exact location of specific atoms within tiny nanoelectronic structures, for example, would enhance designers' insight into manufacture and performance. The ability to directly image the detailed atomic structure of proteins would aid the development of new drugs.

For more than a decade, IBM researchers have been making pioneering advancements in MRFM. With this latest achievement, the team is now able to make images with as few as 10(3) atoms as opposed to the 10(8) atoms required to make an image with today's MRI technology. This improved sensitivity extends MRI into the nanometer realm. (The nanometer realm is typically considered to be at dimensions below 100 nanometers; a nanometer is a billionth of a meter, the length spanned by about 5-10 atoms.)

IBM Research has a distinguished history in developing microscopes for nanoscale imaging and science. Gerd Binnig and Heinrich Rohrer of IBM's Zurich Research Laboratory received the 1986 Nobel Prize in Physics for their invention of the scanning tunneling microscope, which can image individual atoms on electrically conducting surfaces.

The report on this work, "Nuclear magnetic resonance imaging with 90-nm resolution," by H. J. Mamin(1), M. Poggio(1)(2), C. L. Degen(1) and D. Rugar(1) at IBM Research Division(1), Almaden Research Center, San Jose, California and the Center for Probing the Nanoscale, Stanford University(2) will appear in the April 22 issue of Nature Nanotechnology.

(1) IBM Almaden Research Center

(2) Stanford University

####

About IBM Research Division
IBM Research is the world's largest information technology research organization, with about 3,000 scientists and engineers in eight labs in six countries. IBM has produced more research breakthroughs than any other company in the IT industry. For more information on IBM Research, visit http://www.research.ibm.com .

For more information, please click here

Contacts:
Jenny Hunter
IBM
1-408-927-1261


Lizette Kodama
IBM
1-914-945-2703

Copyright © Market Wire

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Discoveries

Researchers find the 'key' to quantum network solution May 25th, 2015

One step closer to a single-molecule device: Columbia Engineering researchers first to create a single-molecule diode -- the ultimate in miniaturization for electronic devices -- with potential for real-world applications May 25th, 2015

DNA Double Helix Does Double Duty in Assembling Arrays of Nanoparticles: Synthetic pieces of biological molecule form framework and glue for making nanoparticle clusters and arrays May 25th, 2015

Engineering Phase Changes in Nanoparticle Arrays: Scientists alter attractive and repulsive forces between DNA-linked particles to make dynamic, phase-shifting forms of nanomaterials May 25th, 2015

Announcements

Researchers find the 'key' to quantum network solution May 25th, 2015

One step closer to a single-molecule device: Columbia Engineering researchers first to create a single-molecule diode -- the ultimate in miniaturization for electronic devices -- with potential for real-world applications May 25th, 2015

DNA Double Helix Does Double Duty in Assembling Arrays of Nanoparticles: Synthetic pieces of biological molecule form framework and glue for making nanoparticle clusters and arrays May 25th, 2015

Engineering Phase Changes in Nanoparticle Arrays: Scientists alter attractive and repulsive forces between DNA-linked particles to make dynamic, phase-shifting forms of nanomaterials May 25th, 2015

Tools

This Slinky lookalike 'hyperlens' helps us see tiny objects: The photonics advancement could improve early cancer detection, nanoelectronics manufacturing and scientists' ability to observe single molecules May 23rd, 2015

Nanometrics Announces Live Webcast of Upcoming Investor and Analyst Day May 20th, 2015

Taking control of light emission: Researchers find a way of tuning light waves by pairing 2 exotic 2-D materials May 20th, 2015

DELMIC announces a workshop hosted by Phenom World on Integrated CLEM to be held on Wednesday June 24th at the Francis Crick Institute (Lincoln Inn Fields Laboratory). May 19th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project