Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Clarkson Physics Prof Synthesizes Brightest Fluorescent Particles Ever

Abstract:
Microscopic Particles Have Applications in Medicine, Forensic Science, Environmental Protection

Clarkson Physics Prof Synthesizes Brightest Fluorescent Particles Ever

Potsdam, NY | Posted on April 3rd, 2007

Clarkson University Physics Professor Igor Sokolov and his team have discovered a method of making the brightest ever synthesized fluorescent silica particles.

These nanostructured macroscopic silica particles have potential applications in medicine, forensic science and environmental protection, among many other uses. Sokolov's research is published in the March 5 issue of the scientific journal Small. You can see the full article at
http://www3.interscience.wiley.com/cgi-bin/fulltext/114088575/HTMLSTART .

Sokolov, along with Ph.D. student Yaroslav Y. Kievsky (now a research fellow at the National Research Council of Canada) and Clarkson undergraduate student Jason M. Kaszpurenko, has created a process to physically entrap a large number of organic fluorescent molecules inside a nanoporous silica matrix. The fluorescence of these particles is 170 times brighter than any particles of similar size created so far. The previous record was reached using quantum dots.

In fluorescence, an initial ignition light energizes molecules, then the molecules reemit the light with a different color. This phenomenon can be used in many different applications because it is easily detectable, using optical filters to remove the ignition light, leaving only the particles' light visible.

There are a multitude of applications for these microscopic "flashlights." These particles, which are less than 1/10th the size of a human hair, could be used like holograms to prove a product's authenticity, imbedded in various objects or fabric for tracking, or used like an "invisible ink" to prove that someone touched an object.

"You could use them like a UPC barcode, encoded and deciphered not in terms of light, but in terms of colors," says Sokolov. "Using only commercially available dyes, you could create and track about 100 trillion combinations of these 'UPC' color barcodes. Because these particles are so bright, it is possible to detect even a single colored particle easily."

There are also potential applications in environmental protection -- dispersing the particles into groundwater to see where it flows to or tracking sources of air pollution. "You could spray these particles into the air like dust," says Sokolov, "and easily collect them because they are so highly visible."

Sokolov sees an ultra-bright future for these fluorescent particles. Down the road he envisions particles that can change color in different acidities. "We have already patented particles that can change color because of temperature change," he says. "The next step is to create a particle that would be a whole laboratory, simultaneously detecting many chemical environment factors -- temperature, acidity, metal ions, etc.

"After that, we could make a nanobot, or smart drug, that would actively react to its environment, and be used, for example, in fighting cancer. Tumor tissue has a higher acidity than the surrounding tissue. As soon as the injected nanobot encountered the high acidity of a tumor, it would start releasing the drug it carries to kill the cancer."

Apart from a family of various sensors, Sokolov's team is now working on scaling down the size of these particles to nanosize (a thousand times smaller than now). "This should have a significant impact in biology," says Sokolov. "For example, you can create particles of different colors. These particles can be made 'sticky' to particular biological molecules inside cells. Then you can see those molecules easily. This fluorescent labeling helps to identify diseased cells and may show exactly what is causing the disease."

Sokolov works on these projects together with postdoctoral fellow Sajo P. Naik and graduate student Dmitry Volkov. Two undergraduate students, Jason M. Kaszpurenko and James O. Benson, both seniors majoring in physics, are also part of the team. "At Clarkson, there are opportunities for undergraduate students in frontier science work like this," says Sokolov. "They are more than welcome to come and work with us."

In fact, Kaszpurenko is a coauthor of the Small journal article and a co-inventor of a patent. Due in part to this undergraduate research experience, Kaszpurenko has been accepted for graduate work at UC Davis, where he will continue his physics studies.

Sokolov received a Ph.D. from Soviet Bureau of Standards (Russian NIST), Russia, and completed his postdoctoral work at the University of Toronto. His research interests include biological physics, Functional Nano/Biomaterials and Interfaces, and atomic force microscopy. Find out more at http://www.clarkson.edu/~isokolov .

Sokolov is part of Clarkson's Center for Advanced Materials Processing (CAMP), which is dedicated to developing Clarkson's research and educational programs in high-technology materials processing and focused on industrial concerns and meeting industrial needs. The Center is built on Clarkson's recognized expertise in colloid and surface science and fine particle technology.

####

About Clarkson University
Clarkson University, located in Potsdam, New York, is a private, nationally ranked university with a reputation for developing innovative leaders in engineering, business, the sciences, health sciences and the humanities. At Clarkson, 3,000 high-ability students excel in an environment where learning is not only positive, friendly and supportive but spans the boundaries of traditional disciplines and knowledge. Faculty achieves international recognition for their research and scholarship and connects students to their leadership potential in the marketplace through dynamic, real-world problem solving.

For more information, please click here

Contacts:
Michael P. Griffin
director of News & Digital Content Services
315-268-6716

Copyright © Clarkson University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Molecular Machines

First 3-D observation of nanomachines working inside cells: Researchers headed by IRB Barcelona combine genetic engineering, super-resolution microscopy and biocomputation to allow them to see in 3-D the protein machinery inside living cells January 27th, 2017

Micro-bubbles make big impact: Research team develops new ultrasound-powered actuator to develop micro robot November 25th, 2016

Scientists come up with light-driven motors to power nanorobots of the future: Researchers from Russia and Ukraine propose a nanosized motor controlled by a laser with potential applications across the natural sciences and medicine November 11th, 2016

HKU chemists develop world's first light-seeking synthetic Nanorobot November 9th, 2016

Nanomedicine

New nano approach could cut dose of leading HIV treatment in half February 24th, 2017

Atomic force imaging used to study nematodes: KFU bionanotechnology lab (head - Dr. Rawil Fakhrullin) has obtained 3-D images of nematodes' cuticles February 23rd, 2017

Nominations Invited for $250,000 Kabiller Prize in Nanoscience: Major international prize recognizes a visionary nanotechnology researcher February 20th, 2017

Good vibrations help reveal molecular details: Rice University scientists combine disciplines to pinpoint small structures in unlabeled molecules February 15th, 2017

Sensors

Strem Chemicals and Dotz Nano Ltd. Sign Distribution Agreement for Graphene Quantum Dots Collaboration February 21st, 2017

Liquid metal nano printing set to revolutionize electronics: Creating integrated circuits just atoms thick February 18th, 2017

Research opens door to smaller, cheaper, more agile communications tech February 16th, 2017

Metamaterial: Mail armor inspires physicists: KIT researchers reverse hall coefficient -- medieval mail armor inspired development of metamaterial with novel properties February 15th, 2017

Discoveries

Sandia use confined nanoparticles to improve hydrogen storage materials performance: Big changes from a small package for hydrogen storage February 25th, 2017

New nano approach could cut dose of leading HIV treatment in half February 24th, 2017

Atom-scale oxidation mechanism of nanoparticles helps develop anti-corrosion materials February 24th, 2017

Atomic force imaging used to study nematodes: KFU bionanotechnology lab (head - Dr. Rawil Fakhrullin) has obtained 3-D images of nematodes' cuticles February 23rd, 2017

Announcements

Dream Chip Technologies Presents First 22nm FD-SOI Silicon of New Automotive Driver Assistance SoC: Advanced driver assistance system (ADAS) computer vision SoC developed for European THINGS2DO project with working first silicon fabricated on GLOBALFOUNDRIES’ 22nm FD-SOI Platfor February 27th, 2017

Sandia use confined nanoparticles to improve hydrogen storage materials performance: Big changes from a small package for hydrogen storage February 25th, 2017

New nano approach could cut dose of leading HIV treatment in half February 24th, 2017

Atom-scale oxidation mechanism of nanoparticles helps develop anti-corrosion materials February 24th, 2017

Environment

Meta-lenses bring benchtop performance to small, hand-held spectrometer: Game-changing nanostructure-based lenses allow smaller devices, increased functionality February 9th, 2017

NIST updates 'sweet' 1950s separation method to clean nanoparticles from organisms January 27th, 2017

Investigating the impact of natural and manmade nanomaterials on living things: Center for Environmental Implications of Nanotechnology develops tools to assess current and future risk January 9th, 2017

PCATDES Starts Field Testing of Photocatalytic Reactors in South East Asia December 28th, 2016

Water

Nano-level lubricant tuning improves material for electronic devices and surface coatings February 11th, 2017

Tough aqua material for water purification: Decontamination of water with a robust and sustainable membrane assembled from 2 synergistically working components January 24th, 2017

Scientists have discovered a new state of matter for water January 2nd, 2017

PCATDES Starts Field Testing of Photocatalytic Reactors in South East Asia December 28th, 2016

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project