Nanotechnology Now

Our NanoNews Digest Sponsors



Heifer International

Wikipedia Affiliate Button


android tablet pc

Home > Press > Clarkson Physics Prof Synthesizes Brightest Fluorescent Particles Ever

Abstract:
Microscopic Particles Have Applications in Medicine, Forensic Science, Environmental Protection

Clarkson Physics Prof Synthesizes Brightest Fluorescent Particles Ever

Potsdam, NY | Posted on April 3rd, 2007

Clarkson University Physics Professor Igor Sokolov and his team have discovered a method of making the brightest ever synthesized fluorescent silica particles.

These nanostructured macroscopic silica particles have potential applications in medicine, forensic science and environmental protection, among many other uses. Sokolov's research is published in the March 5 issue of the scientific journal Small. You can see the full article at
http://www3.interscience.wiley.com/cgi-bin/fulltext/114088575/HTMLSTART .

Sokolov, along with Ph.D. student Yaroslav Y. Kievsky (now a research fellow at the National Research Council of Canada) and Clarkson undergraduate student Jason M. Kaszpurenko, has created a process to physically entrap a large number of organic fluorescent molecules inside a nanoporous silica matrix. The fluorescence of these particles is 170 times brighter than any particles of similar size created so far. The previous record was reached using quantum dots.

In fluorescence, an initial ignition light energizes molecules, then the molecules reemit the light with a different color. This phenomenon can be used in many different applications because it is easily detectable, using optical filters to remove the ignition light, leaving only the particles' light visible.

There are a multitude of applications for these microscopic "flashlights." These particles, which are less than 1/10th the size of a human hair, could be used like holograms to prove a product's authenticity, imbedded in various objects or fabric for tracking, or used like an "invisible ink" to prove that someone touched an object.

"You could use them like a UPC barcode, encoded and deciphered not in terms of light, but in terms of colors," says Sokolov. "Using only commercially available dyes, you could create and track about 100 trillion combinations of these 'UPC' color barcodes. Because these particles are so bright, it is possible to detect even a single colored particle easily."

There are also potential applications in environmental protection -- dispersing the particles into groundwater to see where it flows to or tracking sources of air pollution. "You could spray these particles into the air like dust," says Sokolov, "and easily collect them because they are so highly visible."

Sokolov sees an ultra-bright future for these fluorescent particles. Down the road he envisions particles that can change color in different acidities. "We have already patented particles that can change color because of temperature change," he says. "The next step is to create a particle that would be a whole laboratory, simultaneously detecting many chemical environment factors -- temperature, acidity, metal ions, etc.

"After that, we could make a nanobot, or smart drug, that would actively react to its environment, and be used, for example, in fighting cancer. Tumor tissue has a higher acidity than the surrounding tissue. As soon as the injected nanobot encountered the high acidity of a tumor, it would start releasing the drug it carries to kill the cancer."

Apart from a family of various sensors, Sokolov's team is now working on scaling down the size of these particles to nanosize (a thousand times smaller than now). "This should have a significant impact in biology," says Sokolov. "For example, you can create particles of different colors. These particles can be made 'sticky' to particular biological molecules inside cells. Then you can see those molecules easily. This fluorescent labeling helps to identify diseased cells and may show exactly what is causing the disease."

Sokolov works on these projects together with postdoctoral fellow Sajo P. Naik and graduate student Dmitry Volkov. Two undergraduate students, Jason M. Kaszpurenko and James O. Benson, both seniors majoring in physics, are also part of the team. "At Clarkson, there are opportunities for undergraduate students in frontier science work like this," says Sokolov. "They are more than welcome to come and work with us."

In fact, Kaszpurenko is a coauthor of the Small journal article and a co-inventor of a patent. Due in part to this undergraduate research experience, Kaszpurenko has been accepted for graduate work at UC Davis, where he will continue his physics studies.

Sokolov received a Ph.D. from Soviet Bureau of Standards (Russian NIST), Russia, and completed his postdoctoral work at the University of Toronto. His research interests include biological physics, Functional Nano/Biomaterials and Interfaces, and atomic force microscopy. Find out more at http://www.clarkson.edu/~isokolov .

Sokolov is part of Clarkson's Center for Advanced Materials Processing (CAMP), which is dedicated to developing Clarkson's research and educational programs in high-technology materials processing and focused on industrial concerns and meeting industrial needs. The Center is built on Clarkson's recognized expertise in colloid and surface science and fine particle technology.

####

About Clarkson University
Clarkson University, located in Potsdam, New York, is a private, nationally ranked university with a reputation for developing innovative leaders in engineering, business, the sciences, health sciences and the humanities. At Clarkson, 3,000 high-ability students excel in an environment where learning is not only positive, friendly and supportive but spans the boundaries of traditional disciplines and knowledge. Faculty achieves international recognition for their research and scholarship and connects students to their leadership potential in the marketplace through dynamic, real-world problem solving.

For more information, please click here

Contacts:
Michael P. Griffin
director of News & Digital Content Services
315-268-6716

Copyright © Clarkson University

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Molecular Machines

Creation of 'Rocker' protein opens way for new smart molecules in medicine, other fields December 18th, 2014

Dartmouth researchers create 'green' process to reduce molecular switching waste December 15th, 2014

'Nanomotor lithography' answers call for affordable, simpler device manufacturing October 31st, 2014

Crystallizing the DNA nanotechnology dream: Scientists have designed the first large DNA crystals with precisely prescribed depths and complex 3D features, which could create revolutionary nanodevices October 20th, 2014

Nanomedicine

Creation of 'Rocker' protein opens way for new smart molecules in medicine, other fields December 18th, 2014

Iranian Researchers Produce Electrical Pieces Usable in Human Body December 18th, 2014

Unraveling the light of fireflies December 17th, 2014

First Home-Made Edible Herbal Nanodrug Presented to Pharmacies across Iran December 17th, 2014

Sensors

Promising new method for rapidly screening cancer drugs: UMass Amherst researchers invent fast, accurate new nanoparticle-based sensor system December 15th, 2014

Graphene Applied in Production of Recyclable Electrodes December 13th, 2014

Detecting gases wirelessly and cheaply: New sensor can transmit information on hazardous chemicals or food spoilage to a smartphone December 8th, 2014

Nanosensor to Detect Naproxen Drug Produced in Iran December 6th, 2014

Discoveries

Atom-thick CCD could capture images: Rice University scientists develop two-dimensional, light-sensitive material December 20th, 2014

Oregon researchers glimpse pathway of sunlight to electricity: Collaboration with Lund University uses modified UO spectroscopy equipment to study 'maze' of connections in photoactive quantum dots December 19th, 2014

Instant-start computers possible with new breakthrough December 19th, 2014

Iranian Scientists Use Nanotechnology to Increase Power, Energy of Supercapacitors December 18th, 2014

Announcements

Atom-thick CCD could capture images: Rice University scientists develop two-dimensional, light-sensitive material December 20th, 2014

Oregon researchers glimpse pathway of sunlight to electricity: Collaboration with Lund University uses modified UO spectroscopy equipment to study 'maze' of connections in photoactive quantum dots December 19th, 2014

Instant-start computers possible with new breakthrough December 19th, 2014

Aculon Hires New Business Development Director December 19th, 2014

Environment

Nanoparticles Prove Effective in Removing Phosphor from Calcareous Soil December 10th, 2014

Detecting gases wirelessly and cheaply: New sensor can transmit information on hazardous chemicals or food spoilage to a smartphone December 8th, 2014

Nanocatalysts Can Reduce Pollution Caused by Diesel Engines December 4th, 2014

Green meets nano: Scientists at TU Darmstadt create multifunctional nanotubes using nontoxic materials December 3rd, 2014

Water

Unraveling the light of fireflies December 17th, 2014

Biomimetic dew harvesters: Understanding how a desert beetle harvests water from dew could improve drinking water collection in dew condensers December 8th, 2014

Iranian Scientists Refine Wastewater of Nuclear Power Plants Using Nanoparticles December 1st, 2014

Iranian Experts Clean Uranium-Contaminated Water by Nano-Particles November 23rd, 2014

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project







© Copyright 1999-2014 7th Wave, Inc. All Rights Reserved PRIVACY POLICY :: CONTACT US :: STATS :: SITE MAP :: ADVERTISE