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March 21st, 2007
A novel method of delivering a hydrophobic (water-insoluble) drug, in which the compound effectively acts as its own carrier, has shown comparable efficacy both in vitro and in vivo to the same drug formulated in a conventional delivery vehicle.
US researchers from the University of Buffalo (UB) and the Roswell Park Cancer Institute (RPCI) believe the technique, which could move swiftly into clinical trials, offers significant cost and toxicity advantages over the surfactant or other carrier vehicles commonly used to ensure the stable dispersion of hydrophobic agents into aqueous systems.
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