Nanotechnology Now





Heifer International

Wikipedia Affiliate Button


DHgate

Home > News > The challenge of designing nanomaterials with reduced toxicity

March 1st, 2007

The challenge of designing nanomaterials with reduced toxicity

Abstract:
Obtaining an understanding, at the atomic level, of the interaction of nanomaterials with biological systems has recently become an issue of great research interest. Nanomaterials can exhibit drastically different characteristics compared to their bulk counterparts. Although the use of such materials in biological systems opens avenues for the creation of novel biosensing and alternative nanomedical technologies, these nanomaterials can also be highly toxic. A greater understanding of the interaction of nanomaterials with biological systems, especially of the interaction of nanomaterials with cell membranes, will enable scientists to take full advantage of the unique properties of nanomaterials while minimizing their adverse effects. Fullerenes and their derivatives are an important subset of nanomaterials. Fullerenes have been used as robust oxygen scavengers, anti-HIV drugs, X-ray contrast agents, and transporters for delivering antibodies. While experimental studies suggest that the toxicity of nanomaterials depends critically on their surface properties, it was also found that, in the case of fullerenes, functionalizing the molecules can reduce their toxicity notably. New work by U.S. researchers offers a mechanistic view on the different cytotoxicity of fullerenes and their functionalized derivatives - a first in this important field of nanotoxicity. The major finding is that pristine fullerene can readily jump into a lipid bilayer while the translocation of a functionalized fullerene is severely hindered due to its surface charge, leading to a much reduced toxicity.

Source:
nanowerk.com

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Discoveries

Stanford breakthrough heralds super-efficient light-based computers: Light can transmit more data while consuming far less power than electricity, and an engineering feat brings optical data transport closer to replacing wires May 29th, 2015

Donuts, math, and superdense teleportation of quantum information May 29th, 2015

OSU researchers prove magnetism can control heat, sound: Team leverages OSC services to help confirm, interpret experimental findings May 29th, 2015

New technique speeds nanoMRI imaging: Multiplexing technique for nanoscale magnetic resonance imaging developed by researchers in Switzerland cuts normal scan time from two weeks to two days May 28th, 2015

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers

Stanford breakthrough heralds super-efficient light-based computers: Light can transmit more data while consuming far less power than electricity, and an engineering feat brings optical data transport closer to replacing wires May 29th, 2015

Donuts, math, and superdense teleportation of quantum information May 29th, 2015

OSU researchers prove magnetism can control heat, sound: Team leverages OSC services to help confirm, interpret experimental findings May 29th, 2015

Global Carbon Nanotubes (CNT) Market Expected To Reach USD 3.42 Billion By 2022 May 29th, 2015

Safety-Nanoparticles/Risk management

Statement by QD Vision regarding European Parliament’s Vote on Cadmium-Based Quantum Dots May 20th, 2015

SUNY Poly CNSE and NIOSH Launch Federal Nano Health and Safety Consortium: May 20th, 2015

Cotton fibres instead of carbon nanotubes May 9th, 2015

Nanoparticles in consumer products can significantly alter normal gut microbiome May 4th, 2015

Human Interest/Art

INSIDDE: Uncovering the real history of art using a graphene scanner May 21st, 2015

Winner Announced for NNI’s First ‘EnvisioNano’ Nanotechnology Image Contest May 6th, 2015

To Conserve London's 300-Year-Old Masterpiece, Nanotech & Drones April 12th, 2015

2015 Nanonics Image Contest January 29th, 2015

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More










ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project