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Home > News > Self-heating nanoparticles as tumor-destroying hyperthermia agents

January 22nd, 2007

Self-heating nanoparticles as tumor-destroying hyperthermia agents

Abstract:
Hyperthermia therapy, a form of cancer treatment with elevated temperature in the range of 41-45C, has been recently paid considerable attention because it is expected to significantly reduce clinical side effects compared to chemotherapy and radiotherapy and can be effectively used for killing localized or deeply seated cancer tumors. Accordingly, various forms of hyperthermia have been intensively developed for the past few decades to provide cancer clinics with more effective and advanced cancer therapy techniques. However, in spite of the enormous efforts, all the hyperthermia techniques introduced so far were found to be not effective for completely treating cancer tumors. The low heating temperature owing to the heat loss through a relatively big space gap formed between targeted cells and hyperthermia agents caused by the hard to control agent transport, as well as killing healthy cells attributed to the difficulties of cell differentiations by hyperthermia agents, are considered as the main responsibilities for the undesirable achievements. In a possible breakthrough, researchers in Singapore now report the very promising and successful self-heating temperature rising characteristics of NiFe2O4 nanoparticles. Different from conventional magnetic hyperthermia, in-vivo magnetic nanoparticle hyperthermia is expected to be one of the best solutions for killing tumor cells which are deeply seated and localized inside the human body.

Source:
nanowerk.com

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