Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Unique Collaboration Funded to Develop Nanotechnology for Melanoma

Abstract:
A unique collaboration between electrical engineers, mechanical engineers and cancer researchers may be the perfect combination to improve diagnosis, treatment and follow-up of patients with melanoma.

The National Science Foundation has awarded a $1.1 million, four-year grant to researchers at the University of Colorado Cancer Center, the University of Colorado at Boulder and the University of Texas at Dallas to develop a mechanical system the size of a wristwatch that will display the presence or absence of genetic signals of melanoma.

Unique Collaboration Funded to Develop Nanotechnology for Melanoma

AURORA, CO | Posted on January 17th, 2007

Engineers, working with cancer researchers, will attempt to "wire" and color code various genes using nanotechnology to screen blood samples. The goal is to help physicians and patients visualize changes that occur in melanoma cells that indicate important developments such as disease progression or response to therapy.

The development of a panel of melanoma specific tumor markers through nanotechnology would significantly impact the way melanoma is diagnosed and treated, because the tumor markers could be detected before a tumor had grown large enough to be detected using current imaging technology. Approximately 20 percent of patients who develop malignant melanoma die of metastases present at diagnosis, but not detectable by any current imaging or biochemical techniques. Determination of who has, or will develop cancer, is an important step in the diagnosis, follow-up and treatment of cancer.

Nanomachines can be engineered to sense and pick up molecular markers of cancer cells, enabling scientists to detect molecular changes even when they occur only in a small percentage of cells. The nanoparticles are used to detect the presence of genetic changes and relay the information via electrical connections to doctors and researchers. The connections will produce different colors for different biomarkers.

"Imagine going to your doctor, and with a device the size of a wristwatch, being able to know within five minutes whether or not certain molecular signs of melanoma are present in a blood sample," said Lynne Bemis, PhD, associate professor at UCCC and a lead researcher on the grant. "By ‘seeing' at the very basic level if key biomarkers for melanoma are present and in what capacity, patients and their physicians will have valuable information about cell changes much earlier than current screening technologies do."

Bemis added that a nano device has the potential to not only show changes sooner than current technologies, such as PET (Positron Emission Tomography) Scanning, but would also be cost effective and more efficient. She emphasized that the device is years from its clinical debut, but this grant funding enables researchers to lay the groundwork that is critical to making the device a reality.

"From the engineer's point of view, nanotechnology is very exciting because it enables us to perform a variety of manipulations and operations directly at the size scale of the molecules linked to the disease. Better understanding the interaction of nanomaterials with various biomolecules will open doors to radically new ways to detect and intervene in disease processes," said Won Park, PhD, assistant professor at the University of Colorado at Boulder and the principal investigator of the grant.

Bemis and researchers in the William Robinson lab at the Anschutz Medical Campus in Aurora, Colo., have already identified several biomarkers for Park to build into the panel and color code in collaboration with Jeong-Bong Lee, PhD, associate professor at the University of Texas at Dallas. The UCCC researchers will continue to look for novel biomarkers so that the engineers in Boulder and Dallas can develop a truly comprehensive panel that will provide the most complete information about each patient's tumor. More information on this project can be found at the project's website, http://onchip.colorado.edu .

####

About University of Colorado Cancer Center
The University of Colorado Cancer Center is the only National Cancer Institute-designated comprehensive cancer center in the Rocky Mountain Region. Headquartered primarily at the University of Colorado at Denver and Health Sciences Center, its four-part mission is excellence in cancer research, treatment, prevention and education. For more information, visit the Web site at www.uccc.info or the UCDHSC Newsroom at http://www.uchsc.edu/news/inthenews/

For more information, please click here

Contacts:
Contacts: Jenny Bertrand, UCCC,
(303) 724-3160,

Jim Scott, CU-Boulder, (303) 492-3114,

Copyright © UCHSC

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Nanomedicine

UTSA study describes new minimally invasive device to treat cancer and other illnesses: Medicine diffusion capsule could locally treat multiple ailments and diseases over several weeks December 3rd, 2016

Nanobiotix Provides Update on Global Development of Lead Product NBTXR3: Seven clinical trials across the world: More than 2/3 of STS patients recruited in the “act.in.sarc” Phase II/III trial: Phase I/II prostate cancer trial now recruiting in the U.S. November 28th, 2016

From champagne bubbles, dance parties and disease to new nanomaterials: Understanding nucleation of protein filaments might help with Alzheimer's Disease and type 2 Diabetes November 24th, 2016

Nanopolymer-modified protein array can pinpoint hard-to-find cancer biomarker November 17th, 2016

Announcements

UTSA study describes new minimally invasive device to treat cancer and other illnesses: Medicine diffusion capsule could locally treat multiple ailments and diseases over several weeks December 3rd, 2016

Novel Electrode Structure Provides New Promise for Lithium-Sulfur Batteries December 3rd, 2016

Research Study: MetaSOLTM Shatters Solar Panel Efficiency Forecasts with Innovative New Coating: Coating Provides 1.2 Percent Absolute Enhancement to Triple Junction Solar Cells December 2nd, 2016

Deep insights from surface reactions: Researchers use Stampede supercomputer to study new chemical sensing methods, desalination and bacterial energy production December 2nd, 2016

Human Interest/Art

Weizmann Institute of Science Presents: Weizmann Wonder Wander - 4G - is Online June 21st, 2016

Call for NanoArt and Art-Science-Technology Papers June 9th, 2016

Scientists propose non-animal tools for assessing the toxicity of nanomaterials: Particle and Fibre Toxicology publishes recommendations from expert group meeting April 26th, 2016

Are humans the new supercomputer?Today, people of all backgrounds can contribute to solving serious scientific problems by playing computer games. A Danish research group has extended the limits of quantum physics calculations and simultaneously blurred the boundaries between mac April 14th, 2016

Grants/Awards/Scholarships/Gifts/Contests/Honors/Records

Quantum obstacle course changes material from superconductor to insulator December 1st, 2016

'Back to the Future' inspires solar nanotech-powered clothing November 15th, 2016

2-D material a brittle surprise: Rice University researchers finds molybdenum diselenide not as strong as they thought November 14th, 2016

New Book by Nobel Laureate Tells Story of Chemistry’s New Field: Fraser Stoddart explains the mechanical bond and where it is taking scientists November 11th, 2016

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project