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Home > News > Immune Cell Communication, Cooperation Keys to Hunting Viruses

October 26th, 2006

Immune Cell Communication, Cooperation Keys to Hunting Viruses

Immunologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have used nanotechnology to create a novel “biosensor” to solve in part a perplexing problem in immunology: how immune system cells called killer T-cells hunt down invading viruses.

They found that surprisingly little virus can turn on the killer T-cells, thanks to some complicated communication among so-called “antigen presenting” proteins that recognize and attach to the virus, in turn, making it visible to the immune system. T-cell receptors then “see” the virus, activating the T-cells.

Thomas Jefferson University

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