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July 21st, 2006
Quantum Dot-Peptide Conjugates Image Intracellular Reactions
Abstract:
Using a synthetic peptide modeled after the protein that the human immunodeficiency virus (HIV) uses to enter cells, a multi-institutional research team has created quantum dots that can penetrate the cell membrane and image internal structures in a cell. This research team has also used peptide-coated quantum dots to monitor enzymatic activity within a cell.
In papers published in the journal Bioconjugate Chemistry and Nature Materials, researchers at the U.S. Naval Research Laboratory, Johns Hopkins University, and The Scripps Research Institute reported on their studies of developing a general method for creating self-assembled peptide-quantum dot conjugates for use in a variety of biomedical research applications.
Source:
nano.cancer.gov
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