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Home > News > Dog Virus Nanoparticles Adapted for Tumor Targeting

March 9th, 2006

Dog Virus Nanoparticles Adapted for Tumor Targeting

Abstract:
Writing in the Journal of Nanobiotechnology, a team led by Marianne Manchester, Ph.D., describes its studies aimed at determining whether mass-produced, non-infectious canine parvovirus nanoparticles might be suitable as a tumor-targeting drug delivery vehicle through the particlesí natural interaction with transferrin, a receptor that carries iron into cells. The reproducible size and chemical makeup of virus-based nanoparticles, combined with the relative ease of manufacturing them in large quantities, make them possible winners in the drive to develop nanoparticulate drug carriers for cancer therapy. Such laudable properties are only of use, however, if these protein nanoparticles can be modified to carry small molecules into tumor cells.

Source:
nano.cancer.gov

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