Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > Acrongenomics Announces New Validation Data

Abstract:
Nano-JETA(TM) technology offers great advantages compared to the performance of existing Real Time PCR

Acrongenomics Announces New Validation Data Supporting Nano-JETA Technology as an Ultra-Fast, Robust Method for Nucleic Acid Amplification

Athens, Greece | September 22, 2005

Acrongenomics, Inc. , a research and development nanobiotechnology company focused in the field of nanomolecular diagnostic applications, is pleased to announce a major milestone in further validating its Nano-JETA(TM) technology platform through an alternative method, Gel Electrophoresis, and the subsequent sequencing of the amplified genes. Nano-JETA(TM) technology offers great advantages compared to the performance of existing Real Time PCR by achieving nucleic acid amplification, detection and quantification in greatly reduced time (2 minutes for detection and quantification) with the option for isothermal (one-temperature) and non-isothermal protocols.

According to the validation data, Nano-JETA(TM) technology for Real Time PCR application generated consistent quantitative results from the 1st up to the 13th cycle. To further validate the specific amplification results, another method was used where all the amplified products were analysed by Gel Electrophoresis and documented by the BIO RAD Gel Doc EQ(TM) system. The results of the Gel Electrophoresis proved that the known number copies of genes of interest were amplified, visualized and detected in all copies range of levels studied (10-10,000,000 number of copies).

The Gel Electrophoresis bands of the genes of interest were isolated and sequenced by an independent laboratory and the results proved the specificity of our technology.

Due to the need for quantification from the 1st cycle, a quantification model was developed successfully where calculation of the number of copies is based on a new mathematical algebraic algorithm. Our model has already been tested against the existing approved software programs giving identical results when repeated six times with the same sets of experiments and using the same samples.

In comparison to the widely used PCR-based nucleic acid diagnostics, Nano-JETA(TM) Real Time PCR does not require special instrumentation. Our method validation generated conclusive evidence that Nano-JETA(TM) Technology offers key competitive advantages over conventional Real Time PCR, including:

  • Achieving nucleic acid amplification detection and quantification at greatly reduced time (2 minutes for detection and quantification)
  • Options for isothermal and non-isothermal protocols
  • Increased selectivity, sensitivity and specificity
  • Reproducibility and repeatability
  • Compatibility and simplicity in use

Due to its robustness, speed and simplicity, Nano-JETA(TM) Real Time PCR has the potential to provide researchers and clinicians with highly sensitive, efficient and ultra-fast diagnostic assays that can be used in different diagnostic tests.

####
Contact:
Tom Skarpelos
800-689-8181
info@acrongen.com

Copyright Acrongenomics

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Possible Futures

Sandia researchers make solid ground toward better lithium-ion battery interfaces: Reducing the traffic jam in batteries December 13th, 2017

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

Columbia engineers create artificial graphene in a nanofabricated semiconductor structure: Researchers are the first to observe the electronic structure of graphene in an engineered semiconductor; finding could lead to progress in advanced optoelectronics and data processing December 13th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Nanomedicine

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

Leti to Demo Wristband with Embedded Sensors to Diagnose Sleep Apnea: APNEAband, Which Will Be Demonstrated at CES 2018, Also Monitors Mountain Sickness, Dehydration, Dialysis Treatment Response and Epileptic Seizures December 12th, 2017

Untangling DNA: Researchers filter the entropy out of nanopore measurements December 8th, 2017

Arrowhead Presents New Clinical Data Demonstrating a Sustained Host Response in Hepatitis B Patients Following RNAi Therapy Up to 5.0 log10 reduction in HBsAg observed; data presented at HEP DART 2017 December 6th, 2017

Announcements

A new product to help combat mouldy walls, thanks to technology developed at the ICN2 December 14th, 2017

Sandia researchers make solid ground toward better lithium-ion battery interfaces: Reducing the traffic jam in batteries December 13th, 2017

Perking up and crimping the 'bristles' of polyelectrolyte brushes December 13th, 2017

Columbia engineers create artificial graphene in a nanofabricated semiconductor structure: Researchers are the first to observe the electronic structure of graphene in an engineered semiconductor; finding could lead to progress in advanced optoelectronics and data processing December 13th, 2017

NanoNews-Digest
The latest news from around the world, FREE



  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoTech-Transfer
University Technology Transfer & Patents
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project