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Home > News > Buckyball-Paclitaxel Combination for Aerosolized Drug Delivery

September 6th, 2005

Buckyball-Paclitaxel Combination for Aerosolized Drug Delivery

Abstract:
Nanoscale liposomes have shown promise for delivering anticancer drugs to the lungs, but the effectiveness of such formulations is limited by the rapid clearance of liposomes—and the drugs they contain—from lung tissue. To slow this clearance, a research team led by Lon Wilson, Ph.D., of Rice University, has hooked the nanoparticulate form of molecular carbon, known as fullerenes or buckyballs, to paclitaxel, and incorporated this construct into nanoscale liposomes. Preliminary in vitro data were promising enough that this formulation is now being tested in animal-based tumor models.

Source:
nano.cancer.gov

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