Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button


Home > Press > QBI Life Sciences uses Nanotechnology to advance Drug Discovery

QBI Life Sciences uses Nanotechnology to advance Drug Discovery

Madison, WI | August 10, 2005

Long interested in advancing the process of discovering new treatments for human diseases, the principals of QBI Life Sciences today announced the release of a second polymeric micelle product, PreserveX™-QML-B Polymeric Micelles. PreserveX™ Polymeric Micelles, useful in working with difficult to handle proteins average 21 nanometers in diameter. In the presence of native cell membrane fractions, PreserveX™ Polymeric Micelles self-assemble embedding pieces of cellular membranes in the complex creating multiple particles each providing an environment similar to that of the native membrane. Below is an illustration of this process.

QBI Life Sciences - PreserveX™ Polymeric Micelles
This graphic illustrates the use of PreserveX™ Polymeric Micelles to solubilize membrane proteins and associated lipids from membrane fractions resulting in stabilized micelle/protein/lipid complexes. Copyright © QBI Life Sciences
Click on image for larger version.

The newly released product, PreserveX™-QML-B Polymeric Micelles contains a biotin label enabling the placement of the micelle/protein/lipid complex onto a solid support such as a protein microarray. Below is an illustration of complexes immobilized on a solid support.

QBI Life Sciences - PreserveX™-QML-B
This graphic illustrates the use of PreserveX™-QML-B to immobilize the biotin-labeled micelle/protein/lipid complexes on a surface (bar at the bottom of the graphic) with the use of streptavidin. Once immobilized, ligand binding or enzymatic activity can be determined, or the presence of the protein can be confirmed. Copyright © QBI Life Sciences
Click on image for larger version.

PreserveX™ Polymeric Micelles reflect the combination of polymer chemistry technologies with protein chemistry technologies. Vladimir Trubetskoy, Ph.D., Director of Polymer Chemistry has headed up a team at QBI Life Sciences to develop polymer nano-particles that are useful in working with some of the most difficult to handle proteins. Focusing on membrane proteins (those proteins that reside on, near or embedded in cellular membranes), Dr. Trubetskoy and his team of scientists have come up with a set of very valuable drug discovery tools. In the area of human health, membrane proteins represent 70% of all known drug targets, the agents inside the human body upon which drugs evoke a therapeutic effect. To date, efforts to study these proteins and develop drugs targeting these proteins have been limited.

Announcement of the introduction of PreserveX™-QML-B is coincident with a presentation of product performance at the 2005 Drug Discovery Technology® & Development World Congress in Boston, Massachusetts (link).


About QBI Life Sciences:
QBI Life Sciences is a division of Quintessence Biosciences, Inc. QBI Life Sciences is focused on development and supply of research tools focused on work with membrane proteins. The aim of the Company’s product development efforts is to enable new areas of research.

For more information, please visit

Media Contact:
Ralph Kauten
(608) 441-2950

Copyright © QBI Life Sciences

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Self Assembly

Nanocarriers may carry new hope for brain cancer therapy: Berkeley Lab researchers develop nanoparticles that can carry therapeutics across the brain blood barrier November 22nd, 2015

Light wave technique an advance for optical research November 13th, 2015

One direction: Researchers grow nanocircuitry with semiconducting graphene nanoribbons October 13th, 2015

Making nanowires from protein and DNA September 3rd, 2015


Scientists 'see' detailed make-up of deadly toxin for the first time: Exciting advance provides hope for developing novel potential method of treating pneumococcal diseases such as bacterial pneumonia, meningitis and septicaemia November 25th, 2015

Electric fields remove nanoparticles from blood with ease November 24th, 2015

Production of Nanocapsules Containing Omega-3 Powder in Iran November 24th, 2015

Breakthrough allows tracking of single molecules in 3-D with nanoscale accuracy:New method builds on Nobel Prize-winning technique, with exciting implications for understanding the inner workings of cells and neurons November 23rd, 2015


New 'self-healing' gel makes electronics more flexible November 25th, 2015

Scientists design a QKD-based quantum private query with no failure November 25th, 2015

MIT mathematicians identify limits to heat flow at the nanoscale: New formula identifies limits to nanoscale heat transfer, may help optimize devices that convert heat to electricity November 25th, 2015

Physicists explain the unusual behavior of strongly disordered superconductors: Using a theory they developed previously, the scientists have linked superconducting carrier density with the quantum properties of a substance November 25th, 2015

The latest news from around the world, FREE

  Premium Products
Only the news you want to read!
 Learn More
University Technology Transfer & Patents
 Learn More
Full-service, expert consulting
 Learn More

Nanotechnology Now Featured Books


The Hunger Project

Car Brands
Buy website traffic