Nanotechnology Now

Our NanoNews Digest Sponsors

Heifer International

Wikipedia Affiliate Button

Home > Press > QBI Life Sciences uses Nanotechnology to advance Drug Discovery

QBI Life Sciences uses Nanotechnology to advance Drug Discovery

Madison, WI | August 10, 2005

Long interested in advancing the process of discovering new treatments for human diseases, the principals of QBI Life Sciences today announced the release of a second polymeric micelle product, PreserveX™-QML-B Polymeric Micelles. PreserveX™ Polymeric Micelles, useful in working with difficult to handle proteins average 21 nanometers in diameter. In the presence of native cell membrane fractions, PreserveX™ Polymeric Micelles self-assemble embedding pieces of cellular membranes in the complex creating multiple particles each providing an environment similar to that of the native membrane. Below is an illustration of this process.

QBI Life Sciences - PreserveX™ Polymeric Micelles
This graphic illustrates the use of PreserveX™ Polymeric Micelles to solubilize membrane proteins and associated lipids from membrane fractions resulting in stabilized micelle/protein/lipid complexes. Copyright © QBI Life Sciences
Click on image for larger version.

The newly released product, PreserveX™-QML-B Polymeric Micelles contains a biotin label enabling the placement of the micelle/protein/lipid complex onto a solid support such as a protein microarray. Below is an illustration of complexes immobilized on a solid support.

QBI Life Sciences - PreserveX™-QML-B
This graphic illustrates the use of PreserveX™-QML-B to immobilize the biotin-labeled micelle/protein/lipid complexes on a surface (bar at the bottom of the graphic) with the use of streptavidin. Once immobilized, ligand binding or enzymatic activity can be determined, or the presence of the protein can be confirmed. Copyright © QBI Life Sciences
Click on image for larger version.

PreserveX™ Polymeric Micelles reflect the combination of polymer chemistry technologies with protein chemistry technologies. Vladimir Trubetskoy, Ph.D., Director of Polymer Chemistry has headed up a team at QBI Life Sciences to develop polymer nano-particles that are useful in working with some of the most difficult to handle proteins. Focusing on membrane proteins (those proteins that reside on, near or embedded in cellular membranes), Dr. Trubetskoy and his team of scientists have come up with a set of very valuable drug discovery tools. In the area of human health, membrane proteins represent 70% of all known drug targets, the agents inside the human body upon which drugs evoke a therapeutic effect. To date, efforts to study these proteins and develop drugs targeting these proteins have been limited.

Announcement of the introduction of PreserveX™-QML-B is coincident with a presentation of product performance at the 2005 Drug Discovery Technology® & Development World Congress in Boston, Massachusetts (link).


About QBI Life Sciences:
QBI Life Sciences is a division of Quintessence Biosciences, Inc. QBI Life Sciences is focused on development and supply of research tools focused on work with membrane proteins. The aim of the Company’s product development efforts is to enable new areas of research.

For more information, please visit

Media Contact:
Ralph Kauten
(608) 441-2950

Copyright © QBI Life Sciences

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

Self Assembly

First multicellular organism inspires the design of better cancer drugs September 15th, 2016

A versatile method to pattern functionalized nanowires: A team of researchers from Hokkaido University has developed a versatile method to pattern the structure of 'nanowires,' providing a new tool for the development of novel nanodevices September 9th, 2016

Location matters in the self-assembly of nanoclusters: Iowa State University scientists have developed a new formulation to explain an aspect of the self-assembly of nanoclusters on surfaces that has broad applications for nanotechnology September 8th, 2016

Smarter self-assembly opens new pathways for nanotechnology: Brookhaven Lab scientists discover a way to create billionth-of-a-meter structures that snap together in complex patterns with unprecedented efficiency August 9th, 2016


Nanosciences: Genes on the rack October 21st, 2016

Nanoparticle vaccinates mice against dengue fever October 21st, 2016

Tiny gold particles could be the key to developing a treatment for pancreatic cancer October 19th, 2016

Highly conductive and pure gold nanostructures grown by electron beam induced deposition October 17th, 2016


Nanosciences: Genes on the rack October 21st, 2016

Physicists use lasers to capture first snapshots of rapid chemical bonds breaking October 21st, 2016

Nanoparticle vaccinates mice against dengue fever October 21st, 2016

New perovskite solar cell design could outperform existing commercial technologies: Stanford, Oxford team creates high-efficiency tandem cells October 21st, 2016

The latest news from around the world, FREE

  Premium Products
Only the news you want to read!
 Learn More
University Technology Transfer & Patents
 Learn More
Full-service, expert consulting
 Learn More

Nanotechnology Now Featured Books


The Hunger Project