Home > Press > UCSB Chosen for Two NIH Nanotechnology Grants
UCSB is Only University to Participate in Two PEN Nanotech Grants
Developing Novel Technologies to Diagnose and Treat Diseases of the Heart and Lungs
UCSB Chosen for Two NIH Program of Excellence (PEN) in Nanotechnology Grants
Santa Barbara, CA | July 14, 2005
The University of California, Santa Barbara, has been chosen to participate in two interdisciplinary, multi-university research efforts as a Program of Excellence in Nanotechnology (PEN). The awards by the National Heart, Lung and Blood Institute of the National Institutes of Health (NIH) are part of NIH's strategy to accelerate progress in medical research through innovative technology and interdisciplinary research. Both research efforts bring together bioengineers, materials scientists, biologists and physicians working in interdisciplinary teams.
- UCSB will be working with Washington University in St. Louis and UC Berkeley, under a $12.5 million grant, to develop nanoscale agents to provide early diagnosis and treatment of pulmonary artery disease. At UCSB, the project is being led by Professor Craig Hawker, Director of the Materials Research Lab.
- UCSB will be teaming with The Burnham Institute and Scripps Research Institute, both of La Jolla, Calif., to apply a $13 million grant to develop ways to use nanotechnologies in the design of new ways to detect, monitor, treat and eliminate vulnerable plaque, the probable cause of death from sudden cardiac arrest. UCSB professors participating in the project include Matthew V. Tirrell, PhD, Dean of the college of Engineering and professor of chemical engineering; Andrew N. Cleland, PhD, associate professor pf physics; Patrick Daughterty, PhD, associate professor of chemical engineering; Samir Mitragotri, PhD, assistant professor of chemical engineering; and Joseph Zasadzinski, PhD, professor of chemical engineering.
The team coordinated by Profess Karen L. Wooley at Washington University in St. Louis and led at UCSB by Professor Craig Hawker will use nanoscale materials as carriers for diagnostic systems and to deliver therapeutic agents. A major goal will be to develop ways to trigger a breakdown of the nanoparticles after a payload, such as a drug or antiviral agent, is delivered to a diseased zone. Targeted nanoparticles will search out arteries that are under stress or are diseased.
The group coordinated by The Burnham Institute will build "delivery vehicles" than can be used to transport drugs, imaging agents and nano-devices directly to locations where there is vulnerable plaque; design molecular nano-stents to physically stabilize vulnerable plaque and replace its fibrous cap with an anti-adhesive, anti-inflammatory surface; devise molecular switches that can sense and respond to the pathophysiology of atheroma (fatty deposits on arterial walls); and develop bi-nanoelectromechanical systems (called BioNEMS) that can sense and respond to vulnerable plaque, ultimately providing diagnostic and therapeutic capability.
Barbara Bronson Gray
Copyright © UCSB
If you have a comment, please Contact
Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.
Harris & Harris Group Notes ABSMaterials' Series B Financing November 22nd, 2013
Harris & Harris Group Letter to Shareholders on Website November 18th, 2013
Harris & Harris Group Reports Financial Statements as of September 30, 2013 November 12th, 2013
Harris & Harris Group Notes CordenPharma's Acquisition of Ancora's Carbohydrate Synthesis Platform and Corporate Name November 7th, 2013
Arrowhead Presents Phase 1 Data on ARC-520 at HepDART 2013 December 9th, 2013
Recycled Plastic Proves Effective in Killing Drug-Resistant Fungi: IBN and IBM discover new medical application for converted PET bottles December 9th, 2013
Scientists Mulling Possibility of Using Nanostructured Bioceramics to Repair Bone Tissue December 9th, 2013
Nanobiotix strengthens its NanoXray pipeline with the launch of NBTX-TOPO development, the first nanotherapeutic with embedded radar: 1 product, 2 skills December 6th, 2013
Nontoxic Quantum Dot Research Improves Solar Cells: Record power-conversion efficiency at Los Alamos from quantum-dot sensitized photovoltaics December 10th, 2013
New Method Presented for Production of Alpha SiAlON Single Phase Nanopowder December 10th, 2013
CWRU engineering researchers report nanoscale energy-efficient switching devices at IEDM 2013 December 9th, 2013
Squeezing transistors really hard generates energy savings December 9th, 2013