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June 1st, 2005
Quantum dots, nanosized fluorescent semiconductor particles, are fast becoming a versatile tool for tracking movements of individual molecules in living systems thanks to their brightness, multiple colors, size, resistance to photobleaching, and commercial availability. Two recent papers highlight additional applications that cancer biologists could find useful.
In a paper published in Nature Medicine, a collaborative team lead by Rakesh Jain, Ph.D, and Dai Fukumura, M.D., Ph.D., both at Harvard Medical School, and Moungi Bawendi, Ph.D., of the Massachusetts Institute of Technology (MIT), detail the use of quantum dots to differentiate tumor cells from perivascular cells and the surrounding matrix and to study various processes that occur during tumor development.
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