Nanotechnology Now

Our NanoNews Digest Sponsors
Heifer International



Home > Press > Nanoliposomes Help Efforts to Cure Bacterial Infections

Abstract:
Iranian researchers from Mashhad University of Medical Sciences applied nanotechnology to treat bacterial infections.

Nanoliposomes Help Efforts to Cure Bacterial Infections

Tehran, Iran | Posted on January 27th, 2015

A nano drug delivery system was designed in this research, which has successful performance against antibiotic-resistant infections. After the completion of animal and human tests, the results of the research can be used in pharmaceutical industries.

In this research, a new drug delivery system has been designed based on nanoliposomes by combining an antibiotic and a natural material, and its antibacterial properties have been investigated against Staphylococcus aureus bacterium. This drug delivery system makes possible the achievement of significant elimination properties and increases the amount and accumulation of antibacterial agents within the bacteria.

Staphylococcus aureus usually responds pretty well to strong antibiotics, including vancomycin and linezolid. However, these antibiotics have intense side effects, and their continuous consumption results in bacteria resistance against the medications. Therefore, it is mandatory to discover new approaches to fight infections caused by methicillin-resistant Staphylococcus aureus bacteria. This study tries to investigate the antibacterial activity of a combination of oleic acid and gentamicin against this bacterium in the two free and nanoliposomal forms. The therapeutic effect of this drug has also been compared to that of vancomycin.

Nanoliposomal form of the designed compound has shown higher antibacterial activity than the free form of the drug. The drug delivery system is able to increase the antibacterial activity of the loaded drug, and to decrease the required dosage of the drug. In addition, it acts faster in the elimination of the bacteria. The interesting point is that the nanoliposomal form is more effective in the prevention and elimination of the bacteria in comparison with vancomycin.

Results of the research have been published in Pharmaceutical Biology, vol. 52, issue 11, 2014, pp. 1423-1428.

####

For more information, please click here

Copyright © Fars News Agency

If you have a comment, please Contact us.

Issuers of news releases, not 7th Wave, Inc. or Nanotechnology Now, are solely responsible for the accuracy of the content.

Bookmark:
Delicious Digg Newsvine Google Yahoo Reddit Magnoliacom Furl Facebook

Related News Press

News and information

Researchers develop artificial building blocks of life March 8th, 2024

How surface roughness influences the adhesion of soft materials: Research team discovers universal mechanism that leads to adhesion hysteresis in soft materials March 8th, 2024

Two-dimensional bimetallic selenium-containing metal-organic frameworks and their calcinated derivatives as electrocatalysts for overall water splitting March 8th, 2024

Curcumin nanoemulsion is tested for treatment of intestinal inflammation: A formulation developed by Brazilian researchers proved effective in tests involving mice March 8th, 2024

Nanomedicine

High-tech 'paint' could spare patients repeated surgeries March 8th, 2024

Researchers develop artificial building blocks of life March 8th, 2024

Curcumin nanoemulsion is tested for treatment of intestinal inflammation: A formulation developed by Brazilian researchers proved effective in tests involving mice March 8th, 2024

The Access to Advanced Health Institute receives up to $12.7 million to develop novel nanoalum adjuvant formulation for better protection against tuberculosis and pandemic influenza March 8th, 2024

Discoveries

What heat can tell us about battery chemistry: using the Peltier effect to study lithium-ion cells March 8th, 2024

Researchers’ approach may protect quantum computers from attacks March 8th, 2024

High-tech 'paint' could spare patients repeated surgeries March 8th, 2024

Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024

Announcements

What heat can tell us about battery chemistry: using the Peltier effect to study lithium-ion cells March 8th, 2024

Curcumin nanoemulsion is tested for treatment of intestinal inflammation: A formulation developed by Brazilian researchers proved effective in tests involving mice March 8th, 2024

The Access to Advanced Health Institute receives up to $12.7 million to develop novel nanoalum adjuvant formulation for better protection against tuberculosis and pandemic influenza March 8th, 2024

Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024

Interviews/Book Reviews/Essays/Reports/Podcasts/Journals/White papers/Posters

Researchers develop artificial building blocks of life March 8th, 2024

How surface roughness influences the adhesion of soft materials: Research team discovers universal mechanism that leads to adhesion hysteresis in soft materials March 8th, 2024

Curcumin nanoemulsion is tested for treatment of intestinal inflammation: A formulation developed by Brazilian researchers proved effective in tests involving mice March 8th, 2024

Nanoscale CL thermometry with lanthanide-doped heavy-metal oxide in TEM March 8th, 2024

NanoNews-Digest
The latest news from around the world, FREE




  Premium Products
NanoNews-Custom
Only the news you want to read!
 Learn More
NanoStrategies
Full-service, expert consulting
 Learn More











ASP
Nanotechnology Now Featured Books




NNN

The Hunger Project